📃 Paper Title: A Multicenter Randomized Noninferiority Trial Comparing GreenLight-XPS Laser Vaporization of the Prostate and Transurethral Resection of the Prostate for the Treatment of Benign Prostatic Obstruction: Two-yr Outcomes of the GOLIATH Study
🧍 Author: James A Thomas
🕒 Year: 2016
📚 Journal: European Urology
🌎 Country: UK
ㅤContext to the study:
Which procedures have shown non-inferiority in both efficacy and safety to TURP for management of benign prostatic obstruction in the short term?
ㅤ✅ Take-home message of study:
The use of GreenLight XPS laser system (GL-XPS) showed non-inferiority in both efficacy and safety to TURP for management of benign prostatic obstruction over the course of two years.
ㅤ Prospective randomised study
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Study participants:
Numbers included: 281, GL-XPS: 139, TURP: 142
Inclusion criteria:
IPSS score of more than or equal to 12
Prostate size of less than or equal to 100 grams
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Key study outcomes:
At the 2-yr follow-up 93% of patients were available for analysis.
The mean IPSS at 24 months: 6.9 GL-XPS vs 5.9 TURP
The mean Q-Max at 24 months: 21.6 GL-XPS vs 22.9 TURP
The Complication free rate at 24 months: 83.6% GL-XPS vs 78.9% TURP
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Study Limitations:
Follow up only for 24 months
No blinding of treatment arms
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